The goal of this observational study is to investigate whether the density of Demodex mites is higher in psoriasis patients treated with biologic agents compared to treatment-naive or topically treated patients. The main question\[s\]it aims to answer are: * Are Demodex mites higher in psoriasis patients treated with biologic agents? * In which localization and with what intensity was demodicosis most common? Participants will be assessed using standardized skin surface biopsy technique in four localization on their face . Researchers will compare demodex intensity per cm² to see if the biologic treatments effects demodex intensity on psoriasis patients.
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The standardized skin surface biopsy (SSSB) technique
Timeframe: 1 month