Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

Inclusion Criteria: * Adult men and women of all races and ethnicities who are 50-80 years of age will be eligible. * Only sedentary adults will be eligible (engaging in structured activity for exercise \<3x/week) for Progressive aerobic exercise or Combined training * Ability to use, and accessibility to, an iPad or computer is required for the Adaptive cognitive training and Combined training. * Fluent in English. * The diagnosis of MCI will first be confirmed at the screening evaluation using the clinical dementia rating (CDR) scale and the Montreal Cognitive Assessment (MoCA). We will also evaluate their ADL using instrumental activities of daily living (IADL) to ensure they have preserved independence in functional abilities despite the cognitive deficits. The primary caregivers will be interviewed (either in person or by phone) for the participants' IADL to corroborate the independent functional status. Exclusion Criteria: * Does not have access to a computer or internet to perform the Cogmed® training AND is unwilling to come to the lab for the training. * Unable to undergo an MRI investigation based on claustrophobia or metal foreign bodies. * Symptomatic heart disease, Coronary artery disease, congestive heart failure, uncontrolled hypertension, uncontrolled diabetes (HbA1c\>10%), significant cardiovascular disorders (on EKG and graded exercise test) that would prevent the participant from the exercise training; neurologic, musculoskeletal, or other condition that…