The Safety and Tolerability of CLZ-2002 in Patients With Charcot-Marie Tooth Disease.

Inclusion Criteria: * Subjects aged 18 years or older * Subjects with a proven diagnosis of Charcot-Marie-Tooth disease type 1 at the time of screening visit * Subjects who have muscle weakness in at least foot dorsiflexion (clinical assessment) at the time of screening visit * Subjects with a CMT neuropathy score (CMTNS-v2) of 2 or more and 30 or fewer points at the time of screening visit * Subjects who can understand and are willing to sign a written informed consent document are willing to comply with all study procedures and schedule visits. Exclusion Criteria: * Subjects who have any other neuromuscular diseases * Subjects who have undergone upper and lower limb bone surgery within six months before screening visit * Subjects who have concerns about muscle strength measurements due to the previous surgery * Subjects who have severe active infection including severe/purulent cellulitis at the injection sites at screening visit * Subjects who have a history of hospitalization due to hypersensitivity to antihistamines or allergy or hypersensitivity to certain substances such as food or drugs * Subjects who have a history of unstable cardiovascular disease defined by the presence of myocardial infarction (STEMI or NSTEMI) within 6 months before the screening or the presence of unstable angina pectoris (in the case of increased frequency of symptoms, increased severity, or signs of prolonged symptoms at moderate activity or rest) * Subjects who have a history of a transie…