CompletedNot Applicable

Comparison Between HA330 Hemoperfusion Filter Hemodialysis and Conventional High-Flux Hemodialysis Filter

Indonesia33 participantsStarted 2023-06-16

Plain-language summary

The purpose of this study is to compare the effectiveness between conventional hemodialysis and hemodialysis using hemoperfusion adsorbents in renal dysfunction caused by sepsis

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients age 18 - 65 years old * Patients diagnosed with sepsis with acute kidney injury whose indicated for hemodialysis. Including fluid overload, life-threatening metabolic acidosis, hypercalcemia, pulmonary edema, and uremic Exclusion Criteria: * Patients with hemodynamic instability who need norepinephrine more than 0.5 microgram/kg/minute * Patients denied to be included in the study

What they're measuring

Change in Interleukin (IL)-1Ra concentration before and after hemodialysis

Timeframe: 1 week

Change in Interleukin (IL)-6 concentration before and after hemodialysis

Timeframe: 1 week

Change in Interleukin (IL)-10 concentration before and after hemodialysis

Timeframe: 1 week

Change in Tumor Necrosis Factor (TNF)-a concentration before and after hemodialysis

Timeframe: 1 week

Trial details

NCT IDNCT05941624

SponsorIndonesia University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-31

View on ClinicalTrials.gov More Renal Dysfunction trials