SuspendedPhase 4

Cost Effectiveness of Various Implant Placement Protocols in the Esthetic Zone

Stopped: Funding difficulties

Switzerland160 participantsStarted 2029-01-01

Plain-language summary

Loss of teeth in the anterior upper jaw significantly affects both well-being and chewing function. Nowadays, dental implants are the treatment of choice for replacing missing teeth with fixed dental prostheses and are often placed in the anterior upper jaw. Depending on various patient-related factors, protocols for the placement of dental implants involve the following time points after tooth extraction: 1. On the same day (immediate implantation) 2. After 1-4 months (early implantation) 3. After more than 4 months (late implantation). The different treatment protocols have been investigated over long periods. The choice of the individually suitable treatment protocol for dental implantation depends on many factors and is of utmost importance in order to achieve the best possible treatment outcomes. Selecting an inappropriate treatment protocol would otherwise result in an increased risk of failure. After decades of research and development in dental implantology, an expert association (International Team for Implantology, ITI) published an evidence-based decision management tool in 2022. This decision management tool assists dentists in choosing the individually suitable implant treatment protocol for single-tooth replacement in the upper jaw. A structured examination of the tooth to be extracted allows to classify the situation and select the most suitable treatment protocol for the individual situation. The treatment protocols differ in terms of time and material requirements, which are associated with different costs. There is limited data about the cost-effectiveness of these treatment protocols. The present study aims to assess how the costs of the three treatment protocols differ in relation to treatment success.

Who can participate

Age range20 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 20 years * Willingness and ability to sign informed consent (Appendix Informed Consent Form) and to participate in the study * Plaque index according to Silness and Loe of \< 35% * Presence of a single tooth (FDI positions 15 - 25) that has to be extracted * Sufficient vertical interocclusal space for the placement of an implant crown (FDI regions 13-23: 3 mm, FDI regions 15, 14, 24, 25: 6 mm) * Ridge height sufficient for the placement of a ≥ 8 mm-long implant * Sufficient ridge width for the placement of a 2.9 mm diameter implant (min. 5 mm) Exclusion Criteria: * Any physical or mental disorder that would interfere with the ability to perform adequate oral hygiene or the capability of providing written informed consent and compliance to the protocol * Any disorder that would interfere with wound healing or represent a contraindication for implant surgery such as, but not limited to, uncontrolled diabetes or conditions resulting in or requiring immunosuppression, radiation, chemotherapy, frequent use of antibiotics or antiresorptive medication such as bisphosphonates * Pregnancy (pregnancy tests will be applied; see chapter 6.5) * Intention to become pregnant between inclusion and implant loading * Heavy smoking habit with ≥ 10 cig/d * Allergy to titanium * Severe bruxism or clenching habits, present oro-facial pain * Insufficient ridge width/height for the study implant

What they're measuring

Treatment costs

Timeframe: From enrollment to the 1 year follow-up

Implant survival rates

Timeframe: From enrollment to the 1 year follow-up

Trial details

NCT IDNCT05940662

SponsorUniversity of Bern

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2032-01-01