CompletedPhase 2/3

Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution

United States18 participantsStarted 2023-12-12

Plain-language summary

This is a double-masked, placebo-controlled study which will determine the action of NCX 470 ophthalmic solution, 0.1% on aqueous humor dynamic parameters in healthy volunteers or subjects with OHT.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. ≥18 years of age
✓. Either gender
✓. Subjects without glaucoma
✓. Qualifying IOP at Screening Visit

Exclusion criteria

✕. Narrow anterior chamber angles or disqualifying central corneal thickness in either eye
✕. Clinically significant ocular disease in either eye
✕. Uncontrolled systemic disease
✕. Serious hypersensitivity to topical anesthetic eye drops
✕. Subjects with a known hypersensitivity or contraindications to any of the ingredients in the study medications

What they're measuring

Change in AHD

Timeframe: 8 days

Trial details

NCT IDNCT05938699

SponsorNicox Ophthalmics, Inc.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-03-17

View on ClinicalTrials.gov More Open Angle Glaucoma trials