Impact of Respiratory Training in Lymphoma Survivors (NCT05938127) | Clinical Trial Compass
TerminatedNot Applicable
Impact of Respiratory Training in Lymphoma Survivors
Stopped: Low Accrual
United States1 participantsStarted 2024-09-16
Plain-language summary
High-resistance inspiratory muscle strength training (IMST) is a time-efficient (\~5 minutes/day) form of exercise that employs an affordable, handheld device which impedes inspiratory breathing to train the diaphragm and accessory respiratory muscles and has demonstrated improvements in both cardiovascular health (9 mmHg reduction in systolic blood pressure, 45% improvement in vascular endothelial function) and improve exercise tolerance (12% increase in treadmill exercise time) in generally healthy midlife/older adults. Therefore, this approach may circumvent preventative hurdles to exercise, and augment the effects of exercise for capable survivors.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 - 80
* Primary cancer diagnosis of lymphoma
* Able and willing to participate in a supervised exercise program at the Anschutz Health and Wellness Center
* Provides a signed physician exercise clearance form
* SBP \> 120 mmHg
* Completion of curative cancer treatment over 12 months prior (individuals on maintenance therapy will be included)
* Possession of a smartphone compatible with the IMST training application (available on both Android and Apple).
Exclusion Criteria:
* oSecond active cancer diagnosis
* oPlanned active cancer treatment or change in current treatment in the next 6 months
* Severe obesity (BMI \>; 40 kg/m2) or underweight (BMI \<18.5 kg/m2)
* Unstable weight (\>; 3 kg change in body mass in last 3 months)
* Significant metabolic disorder (e.g. diabetes type II)
* Uncontrolled thyroid disease
* Recent changes in hypertensive medication (within last 3 months)
* Any medical condition that would impact the safety of, or participation in, an exercise program, including:
* Significant pulmonary conditions such as chronic obstructive pulmonary disease, emphysema, or interstitial lung disease
* Known cardiovascular disease, significant hypertension (\>180/120), or a recent cardiac event (within past 6 months)
* Orthopedic conditions such as advanced osteoarthritis, mobility-limiting amputations or chronic injuries, or mobility-limiting acute orthopedic injuries
* Advanced rheumatoid arthritis or chronic widesprea…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.