CompletedNot Applicable

Menstrual Cycle Phase Based Training

Canada24 participantsStarted 2023-09-01

Plain-language summary

The primary purpose of this study is to employ state-of-the-art methods to fill current knowledge gaps on the effects of the menstrual cycle on resistance exercise training adaptations. This work will reduce the sex gap present in exercise physiology, improving women's health information by yielding a deeper understanding of the effect of female physiology on exercise adaptations and subsequent health benefits. Employing a unilateral training design, participant's will have their legs randomized to one of four groups: non-exercise control (CON), exercise control (EX), Follicular based training (FOL), Luteal based training (LUT) Researchers will compare these conditions to see if there are greater benefits to prioritizing resistance training around phases of the menstrual cycle,

Who can participate

Age range

18 Years – 30 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women, between the ages of 18 - 30 years (inclusive) * Have a body mass index (BMI) between 18-35 kg·m2 (inclusive) * Be in general good health as assessed by a general health questionnaire * Non-smoking * Regular menstrual cycle (21-35 days, inclusive) * Not using hormonal contraceptives * Willing and able to provide informed consent Exclusion Criteria: * Use of tobacco or related products. * Ineligible to participate in physical activity based on get active questionnaire (GAQ) * Any concurrent medical, orthopedic, or psychiatric condition that, in the opinion of the Investigator, would compromise his/her ability to comply with the study requirements. * Current illnesses which could interfere with the study (e.g. prolonged severe diarrhea, regurgitation, difficulty swallowing) * Use of hormonal contraceptives * Currently pregnant * Training more than 3x/week for the past 6 months. * Have any electronic medical or metal implants * A history of neuromuscular disorders or muscle/bone wasting diseases * The use of any medications known to affect protein metabolism (glucocorticoids, non-steroidal anti-inflammatory medication, or prescription strength acne medication, etc.) * A (family) history of thrombosis * The use of anticoagulant medications * Excessive alcohol consumption (\>21 units/wk) * History of bleeding diathesis, platelet or coagulation disorders, or antiplatelet/anticoagulation therapy

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Muscle Hypertrophy

Timeframe: 16 weeks

Muscular Strength

Timeframe: 16 Weeks

Trial details

NCT IDNCT05936424

SponsorMcMaster University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-11-15

View on ClinicalTrials.gov More Menstrual Cycle trials