ASK-PrEP (Assistance Services Knowledge-PrEP)

Inclusion Criteria: * self-identified transgender woman or MSM * ≥18 years old * verified HIV negative * identified as high risk for HIV based on the Los Angeles County criteria * SUD (injection and non-injection; excluding cannabis (CUD) only For those who have already initiated PrEP there is an additional eligibility criterion: * non-protective prophylaxis defined as missed ≥4 doses of PrEP/week during any week in the previous 30 days * no PrEP care visits in the past 3 months * willing to provide informed consent; and * willing to comply with study requirements. Should a participant be identified as having kidney or liver dysfunction sufficient to contraindicate PrEP use (creatinine clearance \<60 mL/min), that individual will be withdrawn from study participation but may re-screen for eligibility once adequate renal and/or liver function has been established and medically documented (≥60 mL/min). Exclusion Criteria: * does not identify as a trans woman or male who has sex with men * under 18 years of age * HIV positive status * not identified as high risk for HIV based on the Los Angeles County criteria * no verified SUD or only CUD * if already initiated PrEP: PrEP adherent and PrEP care visits in the past 3 months * unwilling to provide informed consent * unwilling to comply with study requirements;