Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults

Inclusion Criteria: * Patients aged 18 years old and above who are admitted to the ICU of UMMC during the study period * Oliguric patients, with the need for improved diuresis at clinician discretion - defined as urine output \<0.5ml/kg/hour Exclusion Criteria: * Patient refusal for participation of study * Patients with known hypersensitivity reaction to aminophylline or furosemide * Patients with history of tachyarrhythmias, seizures, aspartate aminotransferase or alanine aminotransferase \> 3 times normal, or hypothyroidism. Patient with existing peptic ulcer disease or coagulopathy with INR \> 1.5