CompletedNot Applicable

Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0

United States31 participantsStarted 2024-09-03

Plain-language summary

This pilot sensory experiment will examine cooling from comparable concentrations of WS-3 and menthol to determine appropriate concentrations to use in the main study.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years or older * Able to read and write * Used e-cigarettes containing nicotine * Use e-cigs in past 30 days * No strong dislike of the menthol flavor * Urine cotinine ≥200ng/ml * Willing to abstain from tobacco/nicotine use 2 hrs prior to sessions Exclusion Criteria: * Known hypersensitivity to propylene glycol * Pregnant or lactating females * Uncontrolled asthma * Nut/e-liquid flavorant allergy * Current marijuana (tetrahydrocannabinol) vaping + E-cigarette or vaping use Associated Lung Injury (EVALI) symptoms * Dislike of menthol flavor

What they're measuring

Coolness: Score Change in Coolness of Each E-cigarette Condition (16 Conditions in Total)

Timeframe: Following administration of e-cigarette condition 1 (at 10 minutes), then 5 minutes post administration of each e-cigarette condition, up to 85 minutes (condition 16)

Trial details

NCT IDNCT05932693

SponsorYale University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01-09

Results submitted2025-12-05

View on ClinicalTrials.gov More E-Cig Use trials