CompletedPhase 4

Clinical Efficacy and Safety of Loxacon Dietary Supplement Capsules at Patients With Knee Arthrosis

Hungary100 participantsStarted 2023-01-25

Plain-language summary

The study will be a multicenter, randomized, double-blind, follow-up clinical trial. Neither the examining doctor nor the patient knows which capsule they will receive. Just the test unlock the codes after completion. T

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria Must be able to swallow tablets * According to the ACR (American College of Rheumatology) knee arthrosis criteria, knee arthrosis supported by an imaging procedure (comparative knee X-ray). Both in the case of knee involvement, the more complaining knee will be examined! 2. A patient reporting knee pain characteristic of knee arthrosis for at least 3 months, where the VAS value 40-70 mm. 3. With a diagnosis of mild and moderate knee arthrosis. 4. Male or female patients between the ages of 40 and 80. 5. With a BodyMassIndex between 25-35. Exclusion Criteria:EXCLUSION CRITERIA * Intra-articular corticosteroid within 3 months before starting treatment injection. * Intra-articular hyaluronic acid treatment within 6 months or such treatment during the examination treatment. * Physiotherapy treatment received within 3 months prior to the start of the treatment. * NSAID changed within 3 months prior to treatment or during treatment, or chondroprotective treatment. * In inflammatory rheumatological diseases (RA, SPA, APs, crystal arthropathies, etc.) suffering patient. * Knee surgery within 6 months prior to the examination. * Presence of a metal implant in the knee joint. * Patients who had a knee joint injury within 6 months prior to the examination. * Patients with a palpable fluid collection in the knee or Baker's cyst. * Uncooperative patients, patients with inadequate mental or psychological status. Clinical diagnosis of Alzheimer's Disease \-

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Western Ontario and McMaster Universities Arthritis Index (WOMAC)

Timeframe: one year

Visual analog The Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be')

Timeframe: "through study completion, an average of 1 year".

GONIOMETER

Timeframe: "through study completion, an average of 1 year".

Knee Injury and Osteoarthritis Outcome Score (KOOS)

Timeframe: "through study completion, an average of 1 year".

Trial details

NCT IDNCT05925725

SponsorPolyclinic of the Hospitaller Brothers of St. John of God, Budapest

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-05-05

View on ClinicalTrials.gov More Osteo Arthritis Knee trials

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Western Ontario and McMaster Universities Arthritis Index (WOMAC)

Timeframe: one year

Visual analog The Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be')

Timeframe: "through study completion, an average of 1 year".

GONIOMETER

Timeframe: "through study completion, an average of 1 year".

Knee Injury and Osteoarthritis Outcome Score (KOOS)

Timeframe: "through study completion, an average of 1 year".