The study is aimed to phenotype with cardiac MRI the physiological effects of ketone esters on the heart. Patients with heart failure will be recruited and given ketone esters or placebo in a randomized fashion. Cardiac MRI will be performed at baseline and after 12weeks follow up.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing a ketone ester drink in people with heart failure and measuring changes in left ventricular ejection fraction — can you explain what ejection fraction means for my specific situation and whether a change in that number would be meaningful for me?
2Since this trial is listed as 'active, not recruiting,' it sounds like they're no longer accepting new participants — is there any way to find out if similar ketone ester studies are opening up that I might actually be eligible to join?
3This trial is listed as Phase NA, which sometimes applies to studies focused on understanding how something works in the body rather than proving it's a treatment — what does that mean for how much we'd actually know about whether ketone esters are safe or beneficial for someone in my condition?
4Given that this study is looking at a nutritional supplement approach to heart failure, how does that compare to the standard medications or treatments you'd already recommend for me, and should I be considering those first?
5Are there any known risks or interactions between ketone ester supplements and the heart medications I'm already taking that would be worth discussing before I consider anything like this?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Left Ventricular Ejection Fraction
Timeframe: Pre-intervention and up to 12 weeks after intervention