LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer (NCT05923255) | Clinical Trial Compass
RecruitingNot Applicable
LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer
China568 participantsStarted 2023-05-14
Plain-language summary
The goal of this clinical trial is to compare the long-term outcomes of Laparoscopic Ileocecal-Sparing Right Hemicolectomy(LISH) compared to traditional laparoscopic right hemicolectomy(TRH) in the treatment of hepatic flexure colon cancer and proximal transverse colon cancer.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion criteria
✓. Age between 18-75 years old
✓. ASA classification ≤III
✓. Colon adenocarcinoma confirmed by endoscopy and pathological biopsy
✓. Enhanced abdominal CT indicating the primary lesion is located in the hepatic flexure of the colon or proximal transverse colon (proximal 1/3 of the transverse colon)
✓. Preoperative clinical staging: TanyNanyM0
✓. Patients able to understand the study protocol, willing to participate in the research, and providing written informed consent
Exclusion criteria
✕. Preoperative examination indicates synchronous multiple primary colorectal cancers or other diseases requiring bowel segment resection
✕. Preoperative imaging or intraoperative exploration reveals: 1) tumor involving surrounding organs requiring combined organ resection; 2) presence of distant metastasis; 3) inability to perform R0 resection; 4) fused and fixed lymph nodes at the root of the ileocolic vessels
✕. Additional radical surgery following Endoscopic Mucosal Resection (EMR) and Endoscopic Submucosal Dissection (ESD) procedures
✕. History of any other malignant tumor within the last 5 years or familial adenomatous polyposis, except for cured in situ cervical cancer, basal cell carcinoma, papillary thyroid carcinoma, or skin squamous cell carcinoma
✕. Presence of bowel obstruction, bowel perforation, or intestinal bleeding requiring emergency surgery