CompletedNot Applicable

Comparison of Ocular Changes by Surgical Menopause Using Optical Coherence Tomography (OCT)

Turkey (Türkiye)100 participantsStarted 2022-02-12

Plain-language summary

The aim of this study is to investigate the early changes in macular thickness, corneal thickness and intraocular pressure in young women undergoing surgical menopause. Methods: Eye findings of 30 surgical menopausal (Postoperative 3-6 months) and 48 natural menopause and 22 healty women (control) were evaluated using OCT. Women with no known eye disease, no chronic disease (Diabetes Mellitus, Cardiac Disease any Autoimmune disease) and no migraine in addition to non smokers were included in the study. Women using any hormone and obese women ( BMI \>25 kg/m2) were excluded. Macular and corneal thickness and intraocular pressure (IOP) were measured in both eyes of the women

Who can participate

Age range30 Years – 55 Years

SexFEMALE

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Inclusion Criteria: * The patients included in the study were menstruating women with preoperative natural ovarian appearance and benign non ovarian indications, who had undergone hysterectomy and bilateral salpingo-oopherectomy, and had no preoperative menopause complaints. Patients younger than 52 years of age who have undergone oophorectomy are patients whose ovaries have been removed either because of patient anxiety due to a family history of cancer or because of adhesions. * having a healthy child * have consented to participate in the study Exclusion Criteria: * Chronic disease (such as diabetes, heart disease) * History of continuous drug use * Unwillingness to participate in the study Being between the ages of 18-30

What they're measuring

Effect of surgical menopause on corneal and macular thickness

Timeframe: 6 months after hysterectomy and bilateral salpingo-oopherectomy

Trial details

NCT IDNCT05920655

SponsorBatman Training and Research Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2023-06-01