By InvitationNot Applicable

A High-density Microelectrode for Human Neuronal Recordings

United States10 participantsStarted 2025-12-01

Plain-language summary

The purpose of this study is to test the ability of a newly-designed electrode to measure the activity of individual nerve cells (neurons), and collections of nerve cells (local field potentials) in the brain. The study's main goals are to see how well this electrode works compared to standard electrodes and to validate its safety.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any patient undergoing implantation of a Deep Brain Stimulating (DBS) electrode in the Subthalamic nucleus (STN) for the treatment of Parkinson's disease, in whom microelectrode recording is being performed to improve localization of the STN. * Age \> 18 years of age * Able to give independent informed consent Exclusion Criteria: * Microelectrode recording is not indicated * Previous implantation of DBS electrodes in this site * Known allergic reaction to stainless steel or polyimide

What they're measuring

Neuronal Activity

Timeframe: One week after recording in OR completed

Breakage of Electrode

Timeframe: One week after recording in OR completed

Trial details

NCT IDNCT05919160

SponsorCedars-Sinai Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12

View on ClinicalTrials.gov More Parkinson Disease, Idiopathic trials