CompletedNot Applicable

Dehydration Cognition

United States15 participantsStarted 2023-07-05

Plain-language summary

The investigators want to understand the impact of the body losing and gaining water on brain function. Participants will restrict fluids consumed and exercise to lose 5% of body mass. Participants will then be provided fluid equal to the volume lost to consume over 2 hours (recovery). A series of brain function tests will be performed at baseline, following weight loss, and following recovery.

Who can participate

Age range18 Years – 26 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy * Recreationally active * 18-26 years old Exclusion Criteria: * History of cardiovascular, metabolic, respiratory, neural, or renal disease * Hypertensive (systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg) or tachycardic (resting heart rate ≥ 100 bpm) during the screening visit * Taking medication or supplements with a known side effect of affecting physiological responses to exercise (e.g., aspirin, acetaminophen, beta blockers, statins, stimulants, depressants, SSRIs) * Tobacco or nicotine use in the past six months * Current or past musculoskeletal injury impacting physical activity * Study physician discretion based on any other medical condition or medication

What they're measuring

Multitasking test

Timeframe: Upon completion of 5% body mass loss protocol, approximately 2 hours into the trial

Multitasking test

Timeframe: 2 hours following the dehydration cognitive function test, approximately 4.5 hours into the trial

Trial details

NCT IDNCT05916183

SponsorState University of New York at Buffalo

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-22

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