UnknownNot Applicable

Nutrients-fortified Egg Consumption on Eczema Condition in Individuals With Eczema

Singapore41 participantsStarted 2023-03-06

Plain-language summary

The study aims to assess the effects of daily consumption of nutrients-fortified eggs on eczema condition in individuals with eczema. It is hypothesised that daily consumption of nutrients-fortified egg, which is rich in antioxidants, will improve eczema conditions in individuals with eczema as compared to consumption of regular eggs.

Who can participate

Age range

21 Years – 59 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. English-literate and able to give informed consent in English
. Male and female subjects, aged between 21 and 59 inclusive
. Healthy individuals with no comorbidities or on regular medication
. BMI between 18.5-25 kg/m2
. Mild to moderate severity of eczema, which will also be determined using our questionnaires during screening visit

Exclusion criteria

. Significant change in body weight (3 kg or more) in the past 3 months

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in eczema severity using the SCORing Atopic Dermatitis (SCORAD) index

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in eczema severity using the Eczema Area Severity Index (EASI)

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin quality of life assessment using the Dermatology Life Quality Index (DLQI)

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin hydration level using corneometer

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in transepidermal water loss level using tewameter

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin pH level using pH probe

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin sebum level using sebumeter

Trial details

NCT IDNCT05913791

SponsorNational University of Singapore

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-31

View on ClinicalTrials.gov More Eczema, Atopic trials

Plain-language summary

Who can participate

Age range

21 Years – 59 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. English-literate and able to give informed consent in English
. Male and female subjects, aged between 21 and 59 inclusive
. Healthy individuals with no comorbidities or on regular medication
. BMI between 18.5-25 kg/m2
. Mild to moderate severity of eczema, which will also be determined using our questionnaires during screening visit

Exclusion criteria

. Significant change in body weight (3 kg or more) in the past 3 months

What they're measuring

Change in eczema severity using the SCORing Atopic Dermatitis (SCORAD) index

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in eczema severity using the Eczema Area Severity Index (EASI)

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin quality of life assessment using the Dermatology Life Quality Index (DLQI)

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin hydration level using corneometer

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in transepidermal water loss level using tewameter

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin pH level using pH probe

Timeframe: Every 3 weeks (Week 0, Week 3, Week 6, Week 9, Week 12)

Change in skin sebum level using sebumeter