By InvitationNot Applicable

Optimal Strategy for Repair of Type A Acute Aortic Dissection

France900 participantsStarted 2024-01-01

Plain-language summary

Acute type A aortic dissection (TAAD) persists as a clinicopathologic entity with high lethality in the current era. Several procedures are presently used to repair the TAAAD. The objective of this study is to analyze two groups of individuals using a conservative approach through root-sparing and hemiarch techniques in patients who are hospitalized in higher-risk clinical conditions or more aggressive procedures such as root replacement and total arch replacement in low-risk patients.

Who can participate

Age range18 Years – 90 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * TAAD or intramural hematoma involving the ascending aorta * Patients aged \> 18 years * Symptoms started within 7 days from surgery * Primary surgical repair of acute TAAD * Any other major cardiac surgical procedure concomitant with surgery for TAAD. Exclusion Criteria: * Patients aged \< 18 years * Onset of symptoms \> 7 days from surgery * Prior procedure for TAAD * Concomitant endocarditis; * TAAD secondary to blunt or penetrating chest trauma.

What they're measuring

Operative Mortality (OM)

Timeframe: 30-day

Rate of Transient Neurologic Deficit (TND)

Timeframe: 30-day

Rate of permanent Neurologic Deficit (PND)

Timeframe: 30-day

Trial details

NCT IDNCT05912608

SponsorCentre Cardiologique du Nord

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-30

View on ClinicalTrials.gov More Aortic Dissection trials