Effects of Time-restricted Eating and Exercise Training on Skeletal Muscle Mass Quantity, Quality and Function in Postmenopausal Women With Overweight and Obesity

Inclusion Criteria: * Age between 50 and 65 years. * Menopause (Phase +1a) * Body mass index ≥25.0 and \<40 kg/m2 or waist circumference \> 94 cm. * Weight stability (within 3% of screening weight) for \>3 months prior to baseline. * Sedentary lifestyle (\<150 min/week of moderate-vigorous intensity exercise) for \>3 months prior to baseline. * Usual feeding window ≥12 hours. Exclusion Criteria: * History of major adverse cardiovascular events, clinically significant renal, endocrine or neurological disease, bariatric surgery, HIV/AIDS, known inflammatory and/or rheumatologic disease, cancer or other medical condition in which fasting or exercise is contraindicated. * Use of exogenous (sex) hormones (hormone replacement therapy). * Type 1 or type 2 diabetes. * Severe psychiatric disorders, eating disorders, sleep disorders or alcohol abuse. * Regular use of medications or compounds that may affect study results. * Participating in a weight loss or weight control program. * Caregiver of a dependent person who requires frequent nighttime care/sleep interruptions. Shift workers with variable schedules (e.g., nighttime). Frequent travel across time zones during the study period. * Fear of needles and claustrophobia of magnetic resonance imaging (MRI). * Any medical situation that prevents the performance of MRI (pacemakers, prostheses, etc). * Being unable to understand and accept the instructions or the objectives and protocol of the study.