UnknownNot Applicable

Micro and Nanoplastics in Greenhouse Workers: Biomarkers of Exposure and Effect

25 participantsStarted 2024-09

Plain-language summary

MNPLs effects on human health are still preliminary. Workers exposed to plastic residues are exposed constantly to MNPLs. One of these jobs corresponds to greenhouse workers, that could be considered as a population highly exposed to plastics. The objective of the research is to be able to detect MNPLs on body fluids as well as their potential genotoxic and immunological damage.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria of workers exposed to plastic residues: * Working in an operating greenhouse for a period of 1 month or more * Age over 18 years old * Absence of chronic pathology including neoplasia * Absence of infectious disease at the date of sample collection and for a period of more than 2 weeks * Spanish residence Inclusion Criteria of controls : * Age over 18 years old. Matched by age, gender, and lifestyle to the exposed group. * Absence of chronic pathology including neoplasia * Absence of infectious disease at the date of sample collection and for a period of more than 2 weeks * Spanish residence Exclusion Criteria of workers exposed to plastic residues: * Participation in another clinical study * Pregnancy * Unsigned informed consent Exclusion Criteria of controls: * Participation in another clinical study * Pregnancy * Unsigned informed consent

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Biomonitoring study to detect the presence of MNPLs in body fluids

Timeframe: Up to 1 year

Genotoxicity effects of exposure to MNPLs

Timeframe: Up to 1 year

Genotoxicity effects of exposure to MNPLs

Timeframe: up to 1 year

Study of the effects of MNPLs on immune system

Timeframe: Up to 1 year

Trial details

NCT IDNCT05910489

SponsorRicard Marcos

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-01

Contact for this trial

Ricard Marcos

+34 93 586 20 52 ricard.marcos@uab.cat

View on ClinicalTrials.gov More Microplastics trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.