Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments

Inclusion Criteria: * • Patients suffering from symptomatic irreversible pulpitis. * Tooth should give positive response to cold test * Heamostatis should be achieved after complete pulpotomy * Diagnosis is irreversible pulpitis with/without apical periodontitis * The tooth is restorable and free from advanced periodontal disease * Tooth is free from cracks or splits * Patients should be free from any systemic disease that may affect normal healing and predictable outcomes. * Patients who will agree to the consent and will commit to follow-up period. * Patients with mature root (closed apices) * Teeth with no periapical lesion, resorption or widening. * Soft tissues around the tooth are normal with no swelling or sinus tract * Mandibular posterior teeth only will be involved. Exclusion Criteria: * • Patients with immature root apices. * Patients with any systemic disease that may affect normal healing. * Patients with periapical lesions or infections. * If heamostasis couldn't be achieved within 5-10 minutes * Pregnant females. * Patients who could/would not participate in a 6 months follow-up. * Patients with fistula or swelling * Patients with necrotic pulp. * Patients with old age. * Badly destructed teeth * Teeth that are non-restorable * Teeth that require post and core build up