Not Yet RecruitingEarly Phase 1

Evaluation of the Efficacy of Cryotherapy Combined With Intralesional Hepatitis B Virus Vaccine Versus Either Therapy in the Treatment of Multiple Cutaneous Warts :a Comparative Study

60 participantsStarted 2024-08-01

Plain-language summary

1. investigate the efficacy and safety of combined cryotherapy with intralesional HBV vaccine injection in the treatment of multiple common warts. 2. compare the efficacy and safety of the combined treatment versus either therapy in the treatment of multiple cutaneous warts.

Who can participate

Age range

10 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any patients with multiple cutaneous warts of any site. * Patients age above 10 years old * No concurrent systemic or topical treatment of warts Exclusion Criteria: * Pregnancy and lactation. * History of any bleeding, clotting disorder or using anticoagulants * Chronic systemic diseases such as chronic renal failure, hepatic insufficiency, and cardiovascular disorders. * Concurrent use of systemic or topical treatments of warts. * Patients with history of neuropathy or peripheral ischemia. * Patients with signs of inflammation or infection. * Patients with history of a serious systemic or anaphylactic reaction or allergy to a prior dose of HBV vaccine or to any of its components.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Investigate the efficacy and safety of combined cryotherapy with intralesional HBV vaccine injection in the treatment of multiple common warts.

Timeframe: 10 weeks

Compare the efficacy and safety of the combined treatment versus either therapy in the treatment of multiple cutaneous warts.

Timeframe: 10 weeks

Trial details

NCT IDNCT05902624

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-20

Contact for this trial

Maria Awny, Master

01274724482 maria.awny11@gmail.com

View on ClinicalTrials.gov More Cutaneous Warts trials

Who can participate

Age range

10 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Investigate the efficacy and safety of combined cryotherapy with intralesional HBV vaccine injection in the treatment of multiple common warts.

Timeframe: 10 weeks

Compare the efficacy and safety of the combined treatment versus either therapy in the treatment of multiple cutaneous warts.

Timeframe: 10 weeks