UnknownNot Applicable

Nevoid Basal Cell Carcinomas in Gorlin Syndrome

Norway10 participantsStarted 2023-06-01

Plain-language summary

The overall aim of the project is to gain knowledge about the expected course of nevoid basal cell carcinomas and the usefulness of dermatoscopy in young individuals with Gorlin syndrome. Clinical experience and some case-reports suggest that nevoid basal cell carcinomas have an indolent course with slow growth and that they can sometimes regress. However, no systematic research has previously been performed. Increased knowledge about nevoid basal cell carcinomas and the use of dermatoscopy could be of great clinical value in the follow-up and treatment of individuals with nevoid basal cell carcinoma syndrome.

Who can participate

Age range6 Years – 17 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The individual has Gorlin syndrome (clinically and/or genetically diagnosed) * The individual is minimum 6 years and maximum 17 years * The individual has at least three skin lesions clinically compatible with nevoid basal cell carcinomas Exclusion Criteria: * The patient has a psychiatric disorder not compatible with completion of the study examinations * The patient has received topical treatment (imiquimod, 5-fluorouracil, photodynamic therapy and/or cryotherapy) of nevoid basal cell carcinomas during the last three months

What they're measuring

Nevoid basal cell carcinoma size increase

Timeframe: Two years

Dermatoscopy findings

Timeframe: Two years

Trial details

NCT IDNCT05898347

SponsorOslo University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-06-01

View on ClinicalTrials.gov More Basal Cell Carcinoma trials