Not Yet RecruitingNot Applicable

Conventional Versus Left Bundle Branch Pacing in TAVI

Slovenia50 participantsStarted 2023-06-15

Plain-language summary

This randomized study compares the effects of conventional (right ventricular pacing in patients with LVEF ≥ 40% and cardiac resynchronization therapy in patients with LVEF \< 40 %) versus left bundle branch pacing on left ventricular remodelling in patients with reduced left ventricular ejection fraction (\< 50 %) that need permanent pacemaker implantation after transcatheter aortic valve implantation (TAVI).

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Indication for permanent pacemaker implantation after transcatheter aortic valve implantation (during the same hospitalization) * Left ventricular ejection fraction \< 50 %. Exclusion Criteria: * Unsuccessful TAVI procedure with life expectancy \< 1 year * Ischemic cardiomyopathy with interventricular septal fibrosis (at least echocardiographic signs of fibrosis) * Severe kidney failure (glomerular filtration rate \< 30 ml/min) * Previous permanent pacemaker

What they're measuring

Left ventricular ejection fraction

Timeframe: 12 months

Trial details

NCT IDNCT05895097

SponsorUniversity Medical Centre Ljubljana

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-15

View on ClinicalTrials.gov More Aortic Valve Stenosis trials