Not Yet RecruitingNot Applicable

Ameliorating Stroke-induced Hemianopia Via Multisensory Training

United States72 participantsStarted 2026-08

Plain-language summary

This study seeks to determine the extent of the visual capabilities that can be restored in hemianopic stroke patients by a multisensory training technique and evaluate changes in the brain that the training induces. The effectiveness of the technique will be evaluated in two interventional contexts: patients whose blindness is long-standing and stable, and another in which intervention is as soon as possible after the stroke.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>= 18 years old * Homonymous hemianopia diagnosed and referred by a neurologist, confirmed with Humphrey test (Goldmann size V) on first visit. Hemianopia must have been evident for at least 6 months for inclusion in the first experiment and \<1 month for inclusion in the second * Cognitively normal, defined as having normal activities of daily living OR has received a cognitive adjudication of normal through the Wake Forest University School of Medicine or equivalent within the past 12 months * MRI compatible * Has reliable transportation or is able to use transportation provided by the study * English speaking Exclusion Criteria: * Current major medical problems that might independently affect cognition, vision, or interfere with ability to attend study visits. This includes pathology of the retina or optic nerve explanatory of blindness * Unable or unwilling to attend scheduled testing and training sessions, including the 12 month follow up * Current diagnosis of a major neurological disorder that could interfere with the ability to follow task instructions (Dementia, Parkinson's disease, etc.) or that may interfere with the rehabilitation paradigm (uncorrected asymmetric hearing loss, deafness, hemineglect) * Unwilling or unable to provide consent for study participation * Current stroke symptoms deemed exclusionary by a study physician. This will be reviewed on a case-by-case basis by a study physician to determine whether factors may affect…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Clinical Ophthalmological Test Scores

Timeframe: Baseline

Clinical Ophthalmological Test Scores

Timeframe: Day 15

Clinical Ophthalmological Test Scores

Timeframe: Week 8

Clinical Ophthalmological Test Scores

Timeframe: Week 10

Clinical Ophthalmological Test Scores

Timeframe: Week 16

Clinical Ophthalmological Test Scores

Timeframe: Week 48

Clinical Ophthalmological Test Scores

Timeframe: Week 50

Clinical Ophthalmological Test Scores

Timeframe: Week 56

Trial details

NCT IDNCT05894434

SponsorWake Forest University Health Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-07

Contact for this trial

Benjamin A Rowland, PhD

336-716-7096 benjamin.rowland@advocatehealth.org

View on ClinicalTrials.gov More Hemianopia, Homonymous trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Clinical Ophthalmological Test Scores

Timeframe: Baseline

Clinical Ophthalmological Test Scores

Timeframe: Day 15

Clinical Ophthalmological Test Scores

Timeframe: Week 8

Clinical Ophthalmological Test Scores

Timeframe: Week 10

Clinical Ophthalmological Test Scores

Timeframe: Week 16

Clinical Ophthalmological Test Scores

Timeframe: Week 48

Clinical Ophthalmological Test Scores

Timeframe: Week 50

Clinical Ophthalmological Test Scores

Timeframe: Week 56