RecruitingNot Applicable

Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals

Denmark300 participantsStarted 2023-12-14

Plain-language summary

The investigators recently demonstrated a increase in liver fat in early middle-aged LBW compared to normal birth weight (NBW) men, and 20% of the LBW - but none of the normal birth weight (NBW) - men had previously unknown non-alcoholic fatty liver disease (NAFLD). Here the investigators will further examine the Increased risk of non-alcoholic fatty liver disease in low birth weight individuals by performing a validation study.

Who can participate

Age range35 Years – 40 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 250 healthy, men and women born with a low birth weight (birth weight (BW) \<10% of the population) and 50 born with a normal birth weight controls (BW between 50-90% of the population) * born at term (weeks 39-41) Exclusion Criteria: * BMI\>35 kg/m2 * Disease/medication known to affect primary outcome * Self-reported high physical activity level * Alcohol intake above general recommendations. * Metabolic/liver disease * Weight gain/loss of \>3 kg within the past 6 months

What they're measuring

Liver fat content

Timeframe: 0 minutes

Trial details

NCT IDNCT05890365

SponsorSteno Diabetes Center Copenhagen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06

Contact for this trial

Charlotte Brøns, PhD

+4526129093 charlotte.broens.01@regionh.dk

View on ClinicalTrials.gov More Non-Alcoholic Fatty Liver Disease trials