Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD (NCT05874999) | Clinical Trial Compass
CompletedNot Applicable
Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD
Sweden32 participantsStarted 2022-03-07
Plain-language summary
High-intensity exercise is essential for optimal development of cardiorespiratory fitness and health. This is, however, challenging for most people with chronic obstructive pulmonary disease (COPD) due to ventilatory limitations, leading to exercise at lower intensities accompanied by suboptimal stress on the cardiovascular and muscular system.
The aims of this cross-over trial is:
1. To compare the acute effects of short-duration supramaximal high-intensity interval training (HIIT) vs. traditional moderate-intensity continuous training (MICT) in people with COPD and matched healthy controls (HC).
2. To investigate the feasibility of supramaximal HIIT in people with COPD and matched HC.
3. To compare the cardiorespiratory demand, exercise intensity and symptoms during a modified Borg Cycle Strength Test (BCST) and a cardiopulmonary exercise test (CPET) in people with COPD and HC.
Who can participate
Age range
40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
COPD
Inclusion Criteria:
* COPD with non-reversible airflow obstruction diagnosis (post-bronchodilator forced expiratory volume during the first second/forced vital capacity (FEV1/FVC) \< 0.7)
* Age: \> 40 years
Exclusion Criteria:
* Recent exacerbation of COPD (\< 6 weeks)
* Neuromuscular, orthopaedic and/or any other condition that can compromise participation in testing
* Recent lung cancer (\< 5 years)
* Unstable cardiac disease and/or cardiac stimulator
HC
Inclusion Criteria:
\- Age: \> 40 years
Exclusion Criteria:
* Neuromuscular, orthopaedic and/or any other condition that can compromise participation in testing
* Any respiratory disease
* Recent lung cancer (\< 5 years)
* Unstable cardiac disease and/or cardiac stimulator
* Too low or high physical activity level that prohibits matching
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.