The goal of this clinical trial is to learn about the effect of vitamin D in patients with prophylactic therapy for episodic and chronic tension-type headache in amitriptyline or topiramate treatment. The main question it aims to answer are: • What is the effect of vitamin D in patients with prophylactic therapy for episodic and chronic tension-type headache? Patients will have the next selection criteria: * Patients diagnosed by a neurologist in the headache clinic * Criteria for episodic and chronic tension-type headache * Poor clinical response to prophylactic treatment (amitriptyline, topiramate) * Use of at least 1 prophylactic medication or a history of having used them. * Onset of disease between the ages of 18 and 60 * Signature of informed consent The population will be randomly divided into the following 3 treatment groups: * Participants amitriptyline or topiramate treatment. * Patients with placebo (Calcium) + topiramate/amitriptyline, * Participants with vitamin D3/calcium+topiramate/amitriptyline. Researchers will compare the groups to see if vitamin D can decrease the intensity of your headache and therefore have a new therapeutic option.
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Headache Impact Test, HIT-6
Timeframe: 4 months