Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young A… (NCT05847673) | Clinical Trial Compass
CompletedNot Applicable
Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults
United States125 participantsStarted 2023-08-20
Plain-language summary
This trial assesses the acceptability and preliminary efficacy of Empowered, Queer, Quitting, and Living (EQQUAL) smoking-cessation intervention for sexual and gender minority young adult smokers. The prevalence of tobacco use among sexual and gender minority (SGM) young adults is more than twice as high as non-SGM young adults, suggesting that existing SGM-related disparities in tobacco use will persist well into the foreseeable future unless sustained efforts are undertaken to address them. EQQUAL is an online smoking cessation intervention designed specifically for SGM young adult smokers, and may help them quit smoking.
Who can participate
Age range
18 Years – 30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* DEMOGRAPHIC CRITERIA:
* Participants must self-identify being between 18 and 30 years of age
* Participants must self-identify as a sexual and/or gender minority (i.e., a sexual orientation other than straight and/or gender that doesn't match sex assigned at birth)
* Participants must currently reside in the United States, with a United States (US) mailing address, and anticipate remaining in the US for the duration of the study (3 months)
* SMOKING CRITERIA:
* Participants must self-report smoking at least 1 cigarette per day in the 30 days prior to screening
* TREATMENT ACCESSIBILITY:
* Participants must self-report having at least weekly Internet access for the next three months
* Participants must self-report being willing and able to stream audio and video online for this study
* Participants must self-report current use of a personal email account
* Participants must self-report current use of text messaging
* OTHER CRITERIA:
* Participants must self-report that they are interested in participating in the study for themselves (versus \[vs\] someone else)
* Participants must self-report that they have not participated in one of our prior smoking cessation studies
* Participants must self-report that they are comfortable reading, writing, and speaking English
* Participants must self-report that they understand and agree to the conditions of compensation
* Participants must self-report that they are not currently incarcerated
* Participants must be …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial specifically focused on sexual and gender minority young adults — can you help me understand whether the EQQUAL digital program it studied would be relevant to my background and situation, or whether there are other smoking cessation resources better suited to me?
2The trial measured things like satisfaction and usability rather than long-term health outcomes like cancer prevention — what does that tell us about how much we actually know about whether this program works, and should that affect how much weight I give it compared to other quitting options?
3Since this trial is already completed, is the EQQUAL avatar-based program available for me to use now, or is it still being studied, and how would I even access it if my doctor thought it might help?
4The trial tracked whether people reduced cigarettes per day and stayed nicotine-free for 7 days — do you think those short-term measures are enough to suggest a real benefit, or would you want to see longer follow-up data before recommending something like this over proven treatments like nicotine replacement therapy or prescription medication?
5This was a digital, avatar-led program completed without participants being assigned to a comparison group — does that mean the results are harder to interpret, and is there a more traditional cessation treatment you'd suggest I consider alongside or instead of something like this?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Overall satisfaction
Timeframe: At 3-month follow-up
2
Average change in Contemplation Ladder scores
Timeframe: Baseline through 3-month follow-up
3
Reduction in cigarettes smoked per day
Timeframe: Baseline through 3-month follow-up
4
7-day point prevalence abstinence (PPA) from all nicotine and tobacco use
Timeframe: At 3-month follow-up
5
Usability of the Empowered, Queer, Quitting, and Living (EQQUAL) program