CompletedNot Applicable

Evaluation of the Effect of Leukocyte and Platelet-rich Fibrin on Healing After Periradicular Surgery

Turkey (Türkiye)15 participantsStarted 2022-02-07

Plain-language summary

The aim of this study is to evaluate the effect of two different periapical surgery methods ("curettage+apical resection" and "curettage") on the bone regeneration and clinical healing without applying any material or with applying leukocyte and platelet rich fibrin (L-PRF) to the periradicular intraosseous defect in the treatment of the teeth with large periapical lesions by following the patients for 12 months.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion criteria

✓. Being over 18 years old.
✓. systemic status is ASA I.
✓. No history of allergy to local anesthetics and drugs to be used. D. Absence of a systemic disease or drug use that may adversely affect wound healing and contraindicate oral surgical procedures (radiotherapy, chemotherapy, corticosteroid use, antiplatelet or anticoagulant drug use, connective tissue diseases, vascular diseases, blood dyscrasia, liver diseases, uncontrolled diabetes, etc.).

Exclusion criteria

✕. Having ASA II-III-IV.
✕. Having a history of allergy to local anesthetics and drugs to be used.
✕. Presence of a systemic disease or drug use that may adversely affect postoperative wound healing and periodontal health.

What they're measuring

Apical lesion healing

Timeframe: an average of 1 year

Trial details

NCT IDNCT05847647

SponsorSeyda Ersahan, DDS, PhD

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-02

View on ClinicalTrials.gov More Apical Periodontitis trials