WithdrawnNot Applicable

The Role of Blood Flow Restriction Therapy in Postop Rehabilitation of Foot and Ankle Injuries

Stopped: study never opened

0Started 2026-08

Plain-language summary

The purpose of the study is to determine the role of blood flow restriction (BFR) + neuromuscular electrical stimulation (NMES) in improving post-operative physical therapy and recovery after ankle fracture surgery. We expect to see improved muscle strength, less muscle wasting, and improved functional recovery after surgery when making these additions to routine post-operative (postop) physical therapy protocols.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * isolated, closed low-energy rotational ankle fracture without prior surgery or implants to injured area Exclusion Criteria: * history of Deep Vein Thrombosis in affected extremity * history of significant cardiac disease defined as a recent stent placement in past * history of peripheral arterial disease * history of sickle cell disease * history of coagulopathy * presenting to surgery \>14 days after injury

What they're measuring

Assess for calf muscle atrophy as measured by calf circumference

Timeframe: 2 weeks postop

Assess for calf muscle atrophy as measured by hand held dynamometry

Timeframe: 2 weeks postop

Trial details

NCT IDNCT05844280

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-08

View on ClinicalTrials.gov More Fracture of Foot trials