Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy:

Inclusion Criteria: * Patients aged 18 years or older * Must had clinical diagnosis of sepsis induced encephalopathy. Exclusion Criteria: * Refusal to participate in the study. * Cerebral infection. * Known cerebral lesions (Neoplasm, Traumatic brain injury, Stroke, Ischemic or hemorrhagic cerebrovascular lesions, high intracranial pressure). * Known severe carotid stenosis (\>70％). * Intoxication due to drugs. * Pregnancy. * Patients supported by intra-aortic balloon pumb (IABP).