CompletedNot Applicable

ACT with NMOSD Patients and Caregivers Pilot Study

United States43 participantsStarted 2023-08-01

Plain-language summary

This study will examine the effectiveness of a neuromyelitis optics spectrum disorder (NMOSD) specific Acceptance and Commitment Therapy (ACT) intervention at reducing anxiety and depression in individuals with NMOSD and their caregivers/loved ones and improving overall health outcomes in individuals with NMOSD.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Individuals ages 18 and up with a diagnosis of NMOSD and caregiver loved ones willing to participate in the intervention. * PHQ-9 score \>4, or GAD-7 score \>4 * Webcam access Exclusion Criteria: * History of suicidal attempts or acute suicidal ideation on clinical assessment * Presence of psychotic disorder or symptoms * Presence of psychiatric disorders that interfere with the participation of the study, judged by the study or treating clinician. The presence of other medical conditions that interfere with participation in the study, judged by the study or treating clinician

What they're measuring

Changes in Generalized Anxiety Disorder Questionnaire (GAD7)

Timeframe: Baseline, 6 weeks, and three months after study completion.

Changes in Patient Health Questionnaire (PHQ-9)

Timeframe: Baseline, 6 weeks, and three months after study completion.

Changes in Beck Anxiety Inventory (BAI)

Timeframe: Baseline, 6 weeks, and three months after study completion.

Changes in Beck Depression Inventory (BDI-II)

Timeframe: Baseline, 6 weeks, and three months after study completion.

Trial details

NCT IDNCT05840055

SponsorThomas Jefferson University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-30

View on ClinicalTrials.gov More NMO Spectrum Disorder trials