CompletedNot Applicable

Salt Intake, Hydration Status and Gastrointestinal Discomfort During Fasting

United Kingdom23 participantsStarted 2023-02-14

Plain-language summary

This study is part of a hyperhydration project and it has been designed based on a scoping review (Hyperhydration in healthy adults: a scoping review on different methodologies and vehicles utilized) and a previous study (Dietary patterns and gastrointestinal discomfort during Ramadan in a UK Muslim population). The current study aims to examine the impact of different levels of salt intake (6 \& 9 grams) with \[15 milliliters per kilogram of bodyweight (ml/ kg/ bw)\] of water intake during 7 hours of dry fasting compared to a control group (3g salt) under the state of water balance (euhydrated). A previous study and a review by the authors highlighted the potential negative impact of salt and fasting on gastrointestinal (GI) discomfort; hence, the potential negative side effects on gastrointestinal (GI) discomfort during the intervention period will be investigated. By studying a hyperhydration protocol, this research will help the population to reduce dehydration during dry fasting. By doing so, it may improve the quality of life during Ramadan fasting.

Who can participate

Age range18 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 18 to 45 * BMI between 18.5 and 29.9 * No higher (140/90mmHg) or lower (80/60mmHg) blood pressure * Non-pregnant or lactating * No diabetes (type 1 \& 2) * No gastrointestinal disease such as inflammatory bowel disease (IBD) or Irritable bowel syndrome (IBS) * No disease including the common cold and high cholesterol (total cholesterol above 5 mmol/l) * No covid symptoms * No allergy to the food in the meal list and tomatoes Exclusion Criteria: * Aged \<18 or \>45 years * BMI between \<18.5 or \> 29.9 * Higher (\>140/90mmHg) or lower (\<80/60mmHg) blood pressure * Pregnant or lactating * Having diabetes (type 1 \& 2) * Having gastrointestinal disease such as inflammatory bowel disease (IBD) or Irritable bowel syndrome (IBS) * Having disease including the common cold and high cholesterol (total cholesterol above 5 mmol/l) * Having covid symptoms * Having allergy to the food in the meal list and tomatoes

What they're measuring

Total urine production baseline

Timeframe: 0 hour

Total urine production 1 hour

Timeframe: 1 hour

Total urine production 2 hours

Timeframe: 2 hours

Total urine production 3 hours

Timeframe: 3 hours

Total urine production 4 hours

Timeframe: 4 hours

Total urine production 5 hours

Timeframe: 5 hours

Total urine production 6 hours

Timeframe: 6 hours

Total urine production 7 hours

Timeframe: 7 hours

Body weight baseline

Timeframe: 0 hours

Trial details

NCT IDNCT05839860

SponsorOxford Brookes University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-05-31

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