CXCR4 Targeted PET Imaging in APA Preoperative Localization Diagnosis

Inclusion Criteria: * Patients with PA, confirmed by an elevated aldosterone/renin ratio (ARR) and an intravenous salt loading test. * The patient has provided written informed consent authorisation before participating in the study. * The patient is 18 to 70 years of age at the time of consent. Exclusion Criteria: * Refusal by the patients to undergo 68Ga-PentixaFor PET/CT, AVS, CT, or adrenalectomy. * Suspicion of familial hyperaldosteronism type 1 (FH-1) or type 3 (FH-3). * Suspicion of adrenocortical carcinoma. * Severe comorbidity potentially interfering with treatment or health-related quality of life. * Patients need to take drugs that interfere with clinical research. * Any medical condition present that in the opinion of the investigator will affect patients clinical status. * Pregnancy or lactation. * Estimated glomerular filtration rate \<40mL/min/1.73m2. * Interfering treatment in between 68Ga-PentixaFor PET/CT and AVS.