Specular Microscopy in Patients With Proliferative Diabetic Retinopathy (NCT05838898) | Clinical Trial Compass
UnknownNot Applicable
Specular Microscopy in Patients With Proliferative Diabetic Retinopathy
60 participantsStarted 2023-06-01
Plain-language summary
.1. corneal endothelial profile in patients with proliferative diabetic retinopathy compared to a healthy age-matched control group.
2\. The effect of the age, and duration of Diabetes on the corneal endothelium .
Who can participate
Age range
40 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patients with Type I or II Diabetes Mellitus
.Diagnosed with proliferative diabetic retinopathy . .Intraocular pressure less than 21mmHg.
Healthy controls:
.Healthy individuals aged 40 to 70 years of both sexes. .Intraocular pressure less than 21 mmHg.
Exclusion Criteria:
* Diabetic group:
* Associated ocular diseases that may affect the corneal endothelium such as uveitis, glaucoma, and dystrophy, prolonged CLs use.
* Previous ocular trauma or surgery.
Healthy control:
* Any systemic diseases that may affect corneal endothelium function.
* Associated ocular diseases that may affect the corneal endothelium such as uveitis, glaucoma, and dystrophy, prolonged CLs use.
* Previous ocular trauma , surgery ,laser or intraocular injection.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To predict the effect of Diabetes on the cornea of diabetic patients