RecruitingNot Applicable

Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?

United Arab Emirates300 participantsStarted 2023-05-23

Plain-language summary

To investigate, whether on the day of egg retrieval, after ovarian stimulation for ICSI (intracytoplasmic sperm injection), there is a correlation between the intrafollicular AMH (Anti-Müllerian hormone) levels and the ploidy status of the blastocyst.

Who can participate

Age range

18 Years – 40 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * At least one follicle from each ovary at day of trigger * Age from 18 to 40 years old * Normal menstrual cycle of 25-35 days * Poor, normal and high response will be included * First follicle punctured from each ovary will be consider for inclusion: if the COC (Cumulus Oocyte Complex) is present in clear FF (Follicular fluid), the FF will be collected separately for further analysis and the oocyte included in the study Exclusion Criteria: * Very hematic follicular fluid * If the COC is not found in the follicular fluid * Azoospermia * Known chromosomal abnormalities * Severe OAT (Oligoasthenoteratozoospermia)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Oocyte maturity

Timeframe: 1 day

Fertilization

Timeframe: 1 day

Blastulation

Timeframe: 1 day

Blastocyst quality

Timeframe: 6 days

Ploidy status

Timeframe: 14 days

Mitochondria status

Timeframe: 14 days

Trial details

NCT IDNCT05837325

SponsorART Fertility Clinics LLC

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12-01

Contact for this trial

Barbara Lawrenz, PhD

0097126528000 barbara.lawrenz@artfertilityclinics.com

View on ClinicalTrials.gov More Infertility, Female trials

Who can participate

Age range

18 Years – 40 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.