RecruitingNot Applicable

Microbiome in Head and Neck Squamous Cell Carcinoma

United States60 participantsStarted 2025-05-23

Plain-language summary

This study aims to determine whether dysbiosis actively contributes to HNSCC and if so, the underlying molecular mechanisms.

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Subjects equal to or above the age of 18.
✓. Patients who are seen and evaluated by a provider within the adult Otolaryngology clinic at the University of Colorado Health.
✓. Patients that present with a diagnosis of OSCC.
✓. An equal number of age-matched patients who are visiting the clinic for reasons other than OSCC diagnoses, as the control group.
✓. Ability to understand and willingness to sign a written informed consent document

Characterize human dysbiosis

Timeframe: Day 1

Characterize human metabolomics

Timeframe: Day 1

Integrative multi-omic data analysis and biomarker discovery

Timeframe: Day 365

NCT IDNCT05837221

SponsorUniversity of Colorado, Denver

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-11

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