Effect of Dietary Fiber on Non-dialysis Patients With Chronic Kidney Disease

Inclusion Criteria: * Above 18 years old; * Clinically confirmed (history, blood creatinine, kidney B-ultrasound, laboratory examination, etc.) as stage 3-5 chronic kidney disease, endogenous creatinine clearance was \< 60ml/min according to Cockcroft-Gault formula; * Generally in good condition, have a good understanding of their own illness and physical condition, have self-awareness, and can communicate well with others; * Hemoglobin 100-130g/L; * In a non-dialysis state. * Dietary fiber intake \<25g/d; * Voluntarily join the study, understand the significance of the test and the indicators to be measured, and sign the informed consent. Exclusion Criteria: * Unwilling to join the study; Severe infection: fever, cough and sputum, pharyngeal pain, abdominal pain, diarrhea, carbuncle and other skin and soft tissue infection and other clinical manifestations, blood routine white blood cell count beyond the normal range (10×109/L); * Severe cardiovascular diseases: including chronic cardiac insufficiency grade 3 or above and various arrhythmias; * Obvious hypoproteinemia: albumin less than 30g/L; * Corrective measures for anemia (blood transfusion, erythropoietin, HIF-PHI, iron supplement) have been applied in the past 3 months; * Tumor evidence: certain tumors have been detected or clinical manifestations and tumor markers suggest the possibility of tumor; * Pregnant women; * Recent history of heavy blood loss.