Stopped: No funding received
Anorexia nervosa (AN) and atypical AN (AAN) are severe psychiatric illnesses associated with high disease burden including high treatment costs and excessive mortality rates. Primary characteristics of AN and AAN are food restriction, associated fear of weight gain, and a disturbance in how one's body weight or shape is experienced.The underlying neural mechanisms for the core illness behaviors of food restriction and body size overestimation in anorexia nervosa and atypical anorexia nervosa are not well understood. This project will use neurofeedback and advanced psychophysical methods to assess and moderate the neural and behavioral responses to stress and relate those results to the naturalistic environment. The results will guide the development of novel interventions.
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Functional Magnetic Resonance Imaging (fMRI) brain activation in response to stress during a taste reward task
Timeframe: Difference in brain response between the neutral and stress condition, up to 9 days
Functional Magnetic Resonance Imaging (fMRI) brain activation in response to stress during a body size estimation task
Timeframe: Difference in brain response between the neutral and stress condition, up to 9 days