Active — Not RecruitingNot Applicable

Increasing Adherence to Lung Cancer Screening

United States825 participantsStarted 2023-10-18

Plain-language summary

Investigators are conducting a pragmatic randomized trial testing the effectiveness of patient and clinician nudge strategies on adherence to lung cancer screening (LCS) \& diagnostic follow-up across eligible primary care clinicians \& patients. Following the trial, a subsample of patients \& clinicians will be invited to one-time semi-structured interview \& survey to identify individual \& system-level factors that may restrict or enhance the impact of strategies.

Who can participate

Age range50 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. are practicing primary care or specialty care physicians at a recruiting site within the University of Pennsylvania Health System;
✓. care for patients who completed LCS via LDCT in 2019-2023; and
✓. do not opt-out of study participation.
✓. are eligible for LCS based on 2021 US Preventive Services Task Force (USPSTF) population guidelines (aged 50-80; smoking history of 20-pack years; smoked within the last 15 years)
✓. completed LCS via LDCT in 2019-2023;
✓. have not been diagnosed with lung cancer;
✓. meet criteria for non-adherence;
✓. remain eligible for LCS during the trial enrollment period; and

What they're measuring

Number of completed annual LCS in patients with a negative baseline screen (Lung Imaging Reporting and Data System (Lung-RADS) 1 or 2).

Timeframe: Initial measurement will occur 3 months after randomization

Number of completed recommended diagnostic follow-up scans or procedures in patients with a positive baseline screen (Lung-RADS 3 or 4a).

Timeframe: Initial measurement will occur 3 months after randomization

Trial details

NCT IDNCT05832008

SponsorAbramson Cancer Center at Penn Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-31

View on ClinicalTrials.gov More Lung Cancer trials

Plain-language summary

Who can participate

Age range50 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. are practicing primary care or specialty care physicians at a recruiting site within the University of Pennsylvania Health System;
✓. care for patients who completed LCS via LDCT in 2019-2023; and
✓. do not opt-out of study participation.
✓. are eligible for LCS based on 2021 US Preventive Services Task Force (USPSTF) population guidelines (aged 50-80; smoking history of 20-pack years; smoked within the last 15 years)
✓. completed LCS via LDCT in 2019-2023;
✓. have not been diagnosed with lung cancer;
✓. meet criteria for non-adherence;
✓. remain eligible for LCS during the trial enrollment period; and

What they're measuring

Number of completed annual LCS in patients with a negative baseline screen (Lung Imaging Reporting and Data System (Lung-RADS) 1 or 2).

Timeframe: Initial measurement will occur 3 months after randomization

Number of completed recommended diagnostic follow-up scans or procedures in patients with a positive baseline screen (Lung-RADS 3 or 4a).

Timeframe: Initial measurement will occur 3 months after randomization