Underwater Versus Conventional Endoscopic Mucosal Resection in the Treatment of Non-pedunculated Colorectal Polyps

Inclusion Criteria: * Age \> 18 years * Non-pedunculated polyps of 10 mm or more in size * Type 1 or 2 according to NBI International Colorectal Endoscopy (NICE) classification * Patients must sign an informed consent form prior to registration in study Exclusion Criteria: * Lesions with signs of deep invasion (hard, friable tissue, poor mobility, positive "non-lifting" sign) * Type 3 according to NICE classification * Colorectal cancer * Patients with unstable chronic disease (melitus diabetes, hypertension, heart failure, kidney failure, liver failure, chronic obstructive pulmonary disease) * Hemostasis disorder (INR \> 1.5; platelets \< 100000/mm3)