Consciousness-specific Brain Network Connection of Propofol Sedation and Prolonged Disorders of Consciousness

Inclusion Criteria: * Age 18 - 65 years old, native Chinese speaker, dextromanuality; * Chronic disorder of consciousness; * Spinal cord electrical stimulator implantation under general anesthesia; * Signed informed consent. Exclusion Criteria: * Continuous sedation was administered within 72 hours prior to the study; * Open head injury, parenchymatectomy and other damage of brain structural integrity; * The intracranial compliance decreased due to hydrocephalus and swelling; * Known hearing impairment; * Airway stenosis and various causes of severe ventilation or ventilation dysfunction; * Known or suspected cardiac dysfunction; * Allergic to intravenous general anesthetics; * Associated with other mental or neurological diseases; * Other reasons are not suitable to participate in this study.