CompletedNot Applicable

Flapless Emdogain in the Treatment of Periodontal Residual Pockets

Palestinian Territories48 participantsStarted 2019-09-02

Plain-language summary

48 adult patients participated in a single-centre randomized clinical trial with split- mouth design. They had presented at re-evaluation after initial non-surgical periodontal therapy (steps 1 and 2 of periodontal therapy) for generalized periodontitis with at least 2 teeth with residual probing pocket depths (PPD) ≥5 and ≤8 mm, with bleeding on probing (BOP). Two teeth with similar PPD were randomized to receive re-instrumentation either with (test) or without (control) adjunctive flapless administration of EMD. Differences in the changes of PPD and BOP from baseline to 6 and 12 months will be analysed, and the frequencies of pocket closure (PPD ≤4 mm and no BOP) will be compared

Who can participate

Age range19 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * at least two residual pockets with probing pocket depth (PPD) ≥5 and ≤8 mm, * bleeding on probing (BOP), * mobility ≤degree 1 and * no furcation involvement. Exclusion Criteria: * full mouth plaque score \>20%, * uncontrolled systemic disease, * history of malignant disease in the oral cavity or previous radiotherapy in the head or neck area, * pregnant or lactating females, * drug and alcohol abuse, * smoking \>10 cigarettes per day and * inadequate restorative therapy or malocclusion.

What they're measuring

Differences in changes of probing pocket depths (PPD) from baseline to 6 and 12 months

Timeframe: 12 months

Differences in changes of bleeding on probing (BOP) from baseline to 6 and 12 months

Timeframe: 12 months

Trial details

NCT IDNCT05823389

SponsorArab American University (Palestine)

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-01