Effects of Topical Hyaluronic Acid Gel on Postoperative Pain and Wound Healing

Inclusion Criteria: * Males and females, between 18-70 years of age * Informed Consent Form signed and availability for the duration of the study * Good general health (absence of any condition that, in the opinion of the Principal Investigator, might constitute a risk to the subject while participating in the study * Clinical indication for mucogingival surgery that requires a de-epithelialized gingival graft (DGG) from the palate * Willingness to provide information related to their medical history * Minimum of 10 uncrowned permanent natural teeth (excluding third molars) * Normal salivary flow Exclusion Criteria: * Oral pathology, chronic disease, or a history of allergy to testing products * Subject using anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory medication or daily analgesics within one month prior to the start of the study or scheduled to start such intake during the course of the study * Subject participating in any other clinical study * Subject pregnant or breastfeeding * Subject allergic to oral care products, personal care consumer products, or their ingredients * Extended use of antibiotics or therapeutic mouthwash any time during the three months prior to entry into the study * A medical history reporting that the subject has a current systemic or autoimmune disease, such as diabetes, lupus, etc * Ongoing use of medications known to affect the gingival tissues (i.e. calcium channel blockers, phenytoin, cyclos…