CompletedPhase 2

Re-irradiation for Pelvic Recurrences in Rectal Cancer Patients

Denmark, Norway16 participantsStarted 2015-01

Plain-language summary

This study investigates the potential benefit of re-irradiation of patients with locally advanced rectal recurrences, by a prospective phase II clinical, imaging and translational research study.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Locally recurrent rectal cancer * Previous pelvic RT for rectal cancer and surgery * Potentially resectable by MRI and palpation by MDT evaluation * Absence of non-resectable distant metastases by PET-CT * Age ≥ 18 * Adequate organ function * Acceptable bowel and bladder function * Acceptance for TR sampling Exclusion Criteria: * Central small recurrences deemed immediate resectable * Previous radiotherapy \<12 month prior to recurrence * Non-resectable systemic or regional disease * Unable to undergo MRI or PET-CT * Medical comorbidities precluding radical surgery

What they're measuring

Resection rate

Timeframe: At surgery

Trial details

NCT IDNCT05816980

SponsorAarhus University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-01

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