Evaluation of Perioperative Lung Ultrasound Scores (LUS) in Living Donor Nephrectomy Surgeries (NCT05815888) | Clinical Trial Compass
CompletedNot Applicable
Evaluation of Perioperative Lung Ultrasound Scores (LUS) in Living Donor Nephrectomy Surgeries
Turkey (Türkiye)30 participantsStarted 2023-02-15
Plain-language summary
Living donor nephrectomy surgeries can be performed in lateral position with laparoscopic technique which necessitates pneumoperitoneum. Considering the position and the pneumoperitoneum, lungs can be affected macroscopically. In this study, it is aimed to observe whether lungs are affected by the aforementioned entities. The hypothesis is based on possible deterioration of the lungs due to the physical features of laparoscopic nephrectomy. Lung Ultrasound Score (LUS) will be used to evaluate the actual condition of lungs. Accordingly, one hemithorax is consisted of 6 different zones, and depending on the existence of vertical B lines (that refers to atelectasis and consolidation) each zone is scored 0 to 3. Higher scores reflect worse lung conditions that is associated with the severity of atelectasis. The LUS will be performed at three time points that are 5 minutes after intubation (T1), at the end of surgery and before extubation (T2), and at 30th minute in the postanesthesia care unit (T3). Primary outcome will be the difference between T1 and T3, secondary outcomes will include perioperative blood gas analyses, intraoperative mechanic ventilator parameters, intraoperative total amount of fluid given, postoperative pulmonary complications.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* \>18 years of age
* Kidney donors
* Nephrectomy for transplantation
* Laparoscopic surgery
Exclusion Criteria:
* Chronic obstructive pulmonary disease grade III-IV
* existing structural lung disease (eg. interstitial lung disease)
* Pulmonary hypertension (\>25 mmHg)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial studied lung ultrasound scores in people who donated a kidney — if I'm considering living donor nephrectomy, what do the findings about lung changes between intubation and before extubation mean for my own risk of postoperative lung complications like atelectasis?
2Since this study measured lung ultrasound scores at two specific points during surgery, is lung ultrasound monitoring something my surgical team would use during my procedure, and if not, what tools would they use to watch for breathing problems?
3The trial is completed — has my care team seen or reviewed the results, and do those findings change how they manage breathing and lung health in living kidney donors at this hospital?
4Given that this study focused specifically on postoperative pulmonary complications after donor nephrectomy, are there things about my personal health history, like my breathing or lung function, that would put me at higher risk for these complications?
5Since this was a monitoring and measurement study rather than a treatment trial, are there any practical changes in perioperative lung care for donors that have come out of research like this that I should ask about before agreeing to surgery?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The comparison of T1LUS (After intubation lung ultrasound score) T2LUS (Preextubation Lung ultrasound score)