Porous Titanium Microspheres in Kyphoplasty

Inclusion Criteria: * Presence of osteoporotic vertebral fracture occurred within the previous 6 weeks and documented by CT, MRI, or X-ray in relation to the diagnostic pathway the patient underwent * Patients with fractures according to AO Spine-DGOU OF2, OF3 and OF4 classification are enrollable limited to cases in which soma height loss is less than 60% and in the absence of vertical split type pincer fracture. * Diagnosis of osteoporosis preceding or concurrent with fracture occurrence, regardless of current therapy * Favorable for inclusion in the study with signed informed consent, available for follow-up up to 1 year. * Availability of adequate preoperative radiologic documentation: CT or MRI of the lumbar spine; RX required for evaluation of kyphosis. * Availability of adequate and comprehensive clinical information including presence of ODI score, MRQ, VAS. Exclusion Criteria: * Presence of oncologic, metabolic, or endocrinologic diseases related to bone fragility * Age \< 55 years * Previous treatment of arthrodesis, vertebroplasty, or percutaneous kyphoplasty for previous fractures * Presence of neurological deficits in the lower limbs medullary or radicular prior to fracture occurrence * Unavailability for follow-up for at least 1 year