By InvitationNot Applicable

A Cohort Prospective Study of Predictors Influencing the Quality of Visualization of the Operating Field During Orthognathic Surgery

Russia100 participantsStarted 2023-05-29

Plain-language summary

It is very important to decrease the bleeding during bimaxillary osteotomy in order to increase the visibility of the surgical site. Our primary goal is to investigate the predictive value of pre- and perioperative factors, including controlled hypotension, on visibility of surgical site during bimaxillary osteotomy.

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients refered for bimaxillary osteotomy under general anesthesia with endotracheal intubation; * Anesthesia risk classes (ASA) I and II; * Written statement of informed consent. Exclusion Criteria: * Hypertension as a symptom of hypertensive heart disease or endocrine dysfunction; * Patients receiving antihypertensive drugs; * Patients receiving anticoagulant therapy; * Ischemic heart disease; * Cerebrovascular insufficiency; * Severe hypovolemia; * Anemia; * BMI 30 kg/m2 and higher; * Connective tissue disorders; * Pregnancy; * Participation in other clinical studies; * Recent history of substance abuse (recreational drugs, alcohol); * Allergies to drugs used in the study; * Anxiety requiring psychiatrist supervision and pharmacological therapy.

What they're measuring

Visibility of surgical site

Timeframe: during osteotomy, up to 90 minutes

Trial details

NCT IDNCT05814991

SponsorState Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-01-15

View on ClinicalTrials.gov More Malocclusion trials